| GO:0016874 | 0.970 | 0.921 | | | 0.945 | ligase activity |
| GO:0003700 | 0.977 | 0.876 | | | 0.926 | transcription factor activity |
| GO:0051002 | 0.555 | 0.941 | | | 0.748 | ligase activity, forming nitrogen-metal bonds |
| GO:0051003 | 0.524 | 0.929 | | | 0.726 | ligase activity, forming nitrogen-metal bonds, forming coordination complexes |
| GO:0015666 | 0.990 | 0.379 | | | 0.685 | restriction endodeoxyribonuclease activity |
| GO:0009036 | 0.925 | 0.405 | | | 0.665 | Type II site-specific deoxyribonuclease activity |
| GO:0030528 | 0.999 | 0.281 | | | 0.640 | transcription regulator activity |
| GO:0004871 | 0.998 | 0.182 | | | 0.590 | signal transducer activity |
| GO:0060089 | 1.000 | 0.174 | | | 0.587 | molecular transducer activity |
| GO:0016833 | 0.513 | 0.549 | | | 0.531 | oxo-acid-lyase activity |
| GO:0003677 | 0.963 | 0.087 | | | 0.525 | DNA binding |
| GO:0008907 | 0.991 | 0.044 | | | 0.517 | integrase activity |
| GO:0016775 | 0.986 | 0.033 | | | 0.509 | phosphotransferase activity, nitrogenous group as acceptor |
| GO:0000155 | 0.969 | 0.039 | | | 0.504 | two-component sensor activity |
| GO:0004673 | 0.959 | 0.039 | | | 0.499 | protein histidine kinase activity |
| GO:0004672 | 0.995 | 0.000 | | | 0.498 | protein kinase activity |
| GO:0005515 | 0.913 | 0.069 | | | 0.491 | protein binding |
| GO:0034061 | 0.977 | 0.000 | | | 0.489 | DNA polymerase activity |
| GO:0003887 | 0.958 | 0.000 | | | 0.479 | DNA-directed DNA polymerase activity |
| GO:0008484 | 0.000 | 0.957 | | | 0.479 | sulfuric ester hydrolase activity |