| GO:0016833 | 1.000 | 0.998 | | | 0.999 | oxo-acid-lyase activity |
| GO:0016830 | 1.000 | 0.980 | | | 0.990 | carbon-carbon lyase activity |
| GO:0051537 | 0.913 | 0.995 | | | 0.954 | 2 iron, 2 sulfur cluster binding |
| GO:0005244 | 0.859 | 1.000 | | | 0.930 | voltage-gated ion channel activity |
| GO:0004520 | 0.825 | 0.992 | | | 0.909 | endodeoxyribonuclease activity |
| GO:0016836 | 0.626 | 0.980 | | | 0.803 | hydro-lyase activity |
| GO:0004222 | 0.494 | 1.000 | | | 0.747 | metalloendopeptidase activity |
| GO:0022836 | 0.375 | 0.998 | | | 0.686 | gated channel activity |
| GO:0008234 | 0.254 | 0.999 | | | 0.627 | cysteine-type peptidase activity |
| GO:0005506 | 0.280 | 0.969 | | | 0.624 | iron ion binding |
| GO:0016877 | 0.200 | 0.997 | | | 0.599 | ligase activity, forming carbon-sulfur bonds |
| GO:0008236 | 0.170 | 0.998 | | | 0.584 | serine-type peptidase activity |
| GO:0016788 | 0.194 | 0.967 | | | 0.581 | hydrolase activity, acting on ester bonds |
| GO:0015926 | 0.153 | 0.997 | | | 0.575 | glucosidase activity |
| GO:0042802 | 0.151 | 0.998 | | | 0.575 | identical protein binding |
| GO:0004177 | 0.123 | 0.995 | | | 0.559 | aminopeptidase activity |
| GO:0016628 | 0.092 | 0.988 | | | 0.540 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| GO:0016708 | 0.972 | 0.104 | | | 0.538 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0016849 | 0.076 | 0.998 | | | 0.537 | phosphorus-oxygen lyase activity |
| GO:0016878 | 0.059 | 0.998 | | | 0.529 | acid-thiol ligase activity |