| GO:0050485 | 0.905 | 0.993 | | | 0.949 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0008422 | 0.943 | 0.920 | | | 0.932 | beta-glucosidase activity |
| GO:0046992 | 0.922 | 0.869 | | | 0.895 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0015926 | 0.790 | 0.997 | | | 0.893 | glucosidase activity |
| GO:0016298 | 0.919 | 0.858 | | | 0.888 | lipase activity |
| GO:0016722 | 0.767 | 0.949 | | | 0.858 | oxidoreductase activity, oxidizing metal ions |
| GO:0009036 | 0.578 | 0.952 | | | 0.765 | Type II site-specific deoxyribonuclease activity |
| GO:0016639 | 0.531 | 0.998 | | | 0.764 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| GO:0031419 | 0.499 | 0.998 | | | 0.748 | cobalamin binding |
| GO:0016893 | 0.387 | 0.996 | | | 0.692 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0015293 | 0.746 | 0.623 | | | 0.685 | symporter activity |
| GO:0000150 | 0.426 | 0.921 | | | 0.673 | recombinase activity |
| GO:0004806 | 0.791 | 0.500 | | | 0.646 | triacylglycerol lipase activity |
| GO:0004497 | 0.453 | 0.817 | | | 0.635 | monooxygenase activity |
| GO:0009008 | 0.126 | 0.997 | | | 0.562 | DNA-methyltransferase activity |
| GO:0004190 | 0.105 | 0.998 | | | 0.552 | aspartic-type endopeptidase activity |
| GO:0016641 | 0.677 | 0.392 | | | 0.534 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor |
| GO:0016628 | 0.071 | 0.988 | | | 0.529 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| GO:0015149 | 0.558 | 0.500 | | | 0.529 | hexose transmembrane transporter activity |
| GO:0016765 | 0.057 | 0.991 | | | 0.524 | transferase activity, transferring alkyl or aryl (other than methyl) groups |