| GO:0008276 | 0.691 | 0.994 | | | 0.843 | protein methyltransferase activity |
| GO:0016747 | 0.575 | 0.993 | | | 0.784 | transferase activity, transferring groups other than amino-acyl groups |
| GO:0016741 | 0.521 | 0.977 | | | 0.749 | transferase activity, transferring one-carbon groups |
| GO:0008168 | 0.478 | 0.979 | | | 0.728 | methyltransferase activity |
| GO:0016810 | 0.341 | 0.992 | | | 0.666 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| GO:0015149 | 0.310 | 0.998 | | | 0.654 | hexose transmembrane transporter activity |
| GO:0009008 | 0.480 | 0.725 | | | 0.602 | DNA-methyltransferase activity |
| GO:0015926 | 0.188 | 0.997 | | | 0.593 | glucosidase activity |
| GO:0008415 | 0.178 | 0.990 | | | 0.584 | acyltransferase activity |
| GO:0008757 | 0.161 | 0.984 | | | 0.572 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0016616 | 0.156 | 0.986 | | | 0.571 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| GO:0016614 | 0.152 | 0.976 | | | 0.564 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0042578 | 0.053 | 0.997 | | | 0.525 | phosphoric ester hydrolase activity |
| GO:0016628 | 0.062 | 0.988 | | | 0.525 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| GO:0004826 | 0.021 | 0.999 | | | 0.510 | phenylalanine-tRNA ligase activity |
| GO:0016765 | 0.024 | 0.991 | | | 0.508 | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| GO:0004177 | 0.020 | 0.995 | | | 0.507 | aminopeptidase activity |
| GO:0004536 | 0.006 | 0.995 | | | 0.500 | deoxyribonuclease activity |
| GO:0004549 | 0.000 | 1.000 | | | 0.500 | tRNA-specific ribonuclease activity |
| GO:0016802 | 0.000 | 1.000 | | | 0.500 | trialkylsulfonium hydrolase activity |