| GO:0003677 | 0.724 | 0.950 | | | 0.837 | DNA binding |
| GO:0004518 | 0.436 | 0.996 | | | 0.716 | nuclease activity |
| GO:0005506 | 0.315 | 0.997 | | | 0.656 | iron ion binding |
| GO:0016986 | 0.275 | 0.998 | | | 0.637 | transcription initiation factor activity |
| GO:0009036 | 0.839 | 0.405 | | | 0.622 | Type II site-specific deoxyribonuclease activity |
| GO:0003916 | 0.228 | 0.998 | | | 0.613 | DNA topoisomerase activity |
| GO:0020037 | 0.212 | 0.999 | | | 0.605 | heme binding |
| GO:0016491 | 0.178 | 0.923 | | | 0.551 | oxidoreductase activity |
| GO:0016788 | 0.100 | 0.998 | | | 0.549 | hydrolase activity, acting on ester bonds |
| GO:0017171 | 0.080 | 0.997 | | | 0.539 | serine hydrolase activity |
| GO:0030528 | 0.085 | 0.992 | | | 0.538 | transcription regulator activity |
| GO:0042578 | 0.073 | 0.997 | | | 0.535 | phosphoric ester hydrolase activity |
| GO:0051287 | 0.047 | 0.997 | | | 0.522 | NAD binding |
| GO:0008235 | 0.043 | 0.999 | | | 0.521 | metalloexopeptidase activity |
| GO:0015267 | 0.039 | 0.997 | | | 0.518 | channel activity |
| GO:0016877 | 0.038 | 0.997 | | | 0.518 | ligase activity, forming carbon-sulfur bonds |
| GO:0016810 | 0.033 | 0.992 | | | 0.512 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| GO:0016705 | 0.971 | 0.040 | | | 0.506 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| GO:0000049 | 0.014 | 0.995 | | | 0.505 | tRNA binding |
| GO:0003922 | 0.000 | 1.000 | | | 0.500 | GMP synthase (glutamine-hydrolyzing) activity |