| GO:0008168 | 1.000 | 0.979 | | | 0.990 | methyltransferase activity |
| GO:0016741 | 1.000 | 0.977 | | | 0.989 | transferase activity, transferring one-carbon groups |
| GO:0008233 | 0.942 | 0.993 | | | 0.968 | peptidase activity |
| GO:0004725 | 0.935 | 0.999 | | | 0.967 | protein tyrosine phosphatase activity |
| GO:0009008 | 0.870 | 0.997 | | | 0.934 | DNA-methyltransferase activity |
| GO:0009007 | 0.832 | 0.997 | | | 0.915 | site-specific DNA-methyltransferase (adenine-specific) activity |
| GO:0015925 | 0.832 | 0.997 | | | 0.914 | galactosidase activity |
| GO:0016810 | 0.823 | 0.992 | | | 0.907 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| GO:0015149 | 0.799 | 0.998 | | | 0.898 | hexose transmembrane transporter activity |
| GO:0004527 | 0.754 | 0.996 | | | 0.875 | exonuclease activity |
| GO:0008238 | 0.722 | 0.997 | | | 0.859 | exopeptidase activity |
| GO:0034061 | 0.713 | 0.997 | | | 0.855 | DNA polymerase activity |
| GO:0016817 | 0.737 | 0.921 | | | 0.829 | hydrolase activity, acting on acid anhydrides |
| GO:0005351 | 0.594 | 0.993 | | | 0.793 | sugar:hydrogen symporter activity |
| GO:0042927 | 0.582 | 0.997 | | | 0.789 | siderophore transporter activity |
| GO:0016746 | 0.578 | 0.988 | | | 0.783 | transferase activity, transferring acyl groups |
| GO:0043565 | 0.556 | 0.979 | | | 0.767 | sequence-specific DNA binding |
| GO:0004803 | 0.485 | 0.997 | | | 0.741 | transposase activity |
| GO:0008235 | 0.467 | 0.998 | | | 0.732 | metalloexopeptidase activity |
| GO:0015294 | 0.465 | 0.994 | | | 0.729 | solute:cation symporter activity |