| GO:0004831 | 1.000 | 0.997 | | | 0.999 | tyrosine-tRNA ligase activity |
| GO:0008170 | 0.983 | 0.998 | | | 0.991 | N-methyltransferase activity |
| GO:0016875 | 1.000 | 0.973 | | | 0.986 | ligase activity, forming carbon-oxygen bonds |
| GO:0016876 | 1.000 | 0.972 | | | 0.986 | ligase activity, forming aminoacyl-tRNA and related compounds |
| GO:0008175 | 0.944 | 0.997 | | | 0.971 | tRNA methyltransferase activity |
| GO:0016874 | 0.999 | 0.921 | | | 0.960 | ligase activity |
| GO:0016652 | 0.809 | 0.997 | | | 0.903 | oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor |
| GO:0015926 | 0.567 | 0.997 | | | 0.782 | glucosidase activity |
| GO:0016775 | 0.542 | 0.999 | | | 0.771 | phosphotransferase activity, nitrogenous group as acceptor |
| GO:0003887 | 0.271 | 0.998 | | | 0.634 | DNA-directed DNA polymerase activity |
| GO:0008171 | 0.206 | 0.999 | | | 0.603 | O-methyltransferase activity |
| GO:0004519 | 0.098 | 1.000 | | | 0.549 | endonuclease activity |
| GO:0004300 | 0.098 | 0.998 | | | 0.548 | enoyl-CoA hydratase activity |
| GO:0016491 | 0.061 | 0.998 | | | 0.529 | oxidoreductase activity |
| GO:0016893 | 0.054 | 0.998 | | | 0.526 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0016563 | 0.054 | 0.997 | | | 0.525 | transcription activator activity |
| GO:0016841 | 0.052 | 0.998 | | | 0.525 | ammonia-lyase activity |
| GO:0004540 | 0.045 | 0.996 | | | 0.521 | ribonuclease activity |
| GO:0016846 | 0.034 | 0.999 | | | 0.516 | carbon-sulfur lyase activity |
| GO:0004091 | 0.024 | 0.999 | | | 0.511 | carboxylesterase activity |