| GO:0009036 | 0.984 | 0.999 | | | 0.991 | Type II site-specific deoxyribonuclease activity |
| GO:0050662 | 0.982 | 0.977 | | | 0.979 | coenzyme binding |
| GO:0016855 | 0.771 | 0.998 | | | 0.885 | racemase and epimerase activity, acting on amino acids and derivatives |
| GO:0015666 | 0.636 | 1.000 | | | 0.818 | restriction endodeoxyribonuclease activity |
| GO:0016746 | 0.585 | 0.988 | | | 0.786 | transferase activity, transferring acyl groups |
| GO:0016708 | 0.319 | 0.998 | | | 0.659 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0034061 | 0.176 | 0.999 | | | 0.587 | DNA polymerase activity |
| GO:0016741 | 0.187 | 0.977 | | | 0.582 | transferase activity, transferring one-carbon groups |
| GO:0016866 | 0.134 | 0.996 | | | 0.565 | intramolecular transferase activity |
| GO:0051540 | 0.112 | 0.988 | | | 0.550 | metal cluster binding |
| GO:0051536 | 0.106 | 0.991 | | | 0.549 | iron-sulfur cluster binding |
| GO:0008236 | 0.097 | 0.998 | | | 0.548 | serine-type peptidase activity |
| GO:0016407 | 0.106 | 0.986 | | | 0.546 | acetyltransferase activity |
| GO:0051539 | 0.106 | 0.985 | | | 0.546 | 4 iron, 4 sulfur cluster binding |
| GO:0008233 | 0.089 | 0.993 | | | 0.541 | peptidase activity |
| GO:0003755 | 0.074 | 0.998 | | | 0.536 | peptidyl-prolyl cis-trans isomerase activity |
| GO:0016491 | 0.140 | 0.923 | | | 0.531 | oxidoreductase activity |
| GO:0016903 | 0.057 | 0.998 | | | 0.528 | oxidoreductase activity, acting on the aldehyde or oxo group of donors |
| GO:0022891 | 0.073 | 0.967 | | | 0.520 | substrate-specific transmembrane transporter activity |
| GO:0008430 | 0.041 | 0.998 | | | 0.520 | selenium binding |