| GO:0016853 | 1.000 | 0.970 | | | 0.985 | isomerase activity |
| GO:0003677 | 0.998 | 0.950 | | | 0.974 | DNA binding |
| GO:0016837 | 0.969 | 0.921 | | | 0.945 | carbon-oxygen lyase activity, acting on polysaccharides |
| GO:0016888 | 0.994 | 0.732 | | | 0.863 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0009036 | 0.445 | 0.992 | | | 0.718 | Type II site-specific deoxyribonuclease activity |
| GO:0015666 | 0.997 | 0.379 | | | 0.688 | restriction endodeoxyribonuclease activity |
| GO:0008649 | 0.553 | 0.743 | | | 0.648 | rRNA methyltransferase activity |
| GO:0004519 | 0.299 | 0.987 | | | 0.643 | endonuclease activity |
| GO:0015149 | 0.962 | 0.197 | | | 0.579 | hexose transmembrane transporter activity |
| GO:0016725 | 0.192 | 0.931 | | | 0.561 | oxidoreductase activity, acting on CH or CH2 groups |
| GO:0005337 | 0.872 | 0.248 | | | 0.560 | nucleoside transmembrane transporter activity |
| GO:0016758 | 0.746 | 0.361 | | | 0.553 | transferase activity, transferring hexosyl groups |
| GO:0008234 | 0.232 | 0.826 | | | 0.529 | cysteine-type peptidase activity |
| GO:0004518 | 0.334 | 0.687 | | | 0.510 | nuclease activity |
| GO:0016708 | 0.320 | 0.695 | | | 0.507 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0003916 | 1.000 | 0.000 | | | 0.500 | DNA topoisomerase activity |
| GO:0003918 | 1.000 | 0.000 | | | 0.500 | DNA topoisomerase (ATP-hydrolyzing) activity |
| GO:0004033 | 0.000 | 0.998 | | | 0.499 | aldo-keto reductase activity |
| GO:0004048 | 0.000 | 0.998 | | | 0.499 | anthranilate phosphoribosyltransferase activity |
| GO:0015415 | 0.000 | 0.998 | | | 0.499 | phosphate transmembrane-transporting ATPase activity |