| GO:0005515 | 0.972 | 0.987 | | | 0.980 | protein binding |
| GO:0016722 | 0.909 | 0.996 | | | 0.953 | oxidoreductase activity, oxidizing metal ions |
| GO:0003677 | 0.890 | 0.950 | | | 0.920 | DNA binding |
| GO:0016776 | 0.754 | 0.992 | | | 0.873 | phosphotransferase activity, phosphate group as acceptor |
| GO:0004518 | 0.701 | 0.996 | | | 0.849 | nuclease activity |
| GO:0016708 | 0.688 | 0.998 | | | 0.843 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0005507 | 0.768 | 0.902 | | | 0.835 | copper ion binding |
| GO:0008324 | 0.522 | 0.961 | | | 0.742 | cation transmembrane transporter activity |
| GO:0004803 | 0.490 | 0.987 | | | 0.739 | transposase activity |
| GO:0016879 | 0.487 | 0.979 | | | 0.733 | ligase activity, forming carbon-nitrogen bonds |
| GO:0003887 | 0.886 | 0.550 | | | 0.718 | DNA-directed DNA polymerase activity |
| GO:0046915 | 0.745 | 0.576 | | | 0.661 | transition metal ion transmembrane transporter activity |
| GO:0016817 | 0.398 | 0.921 | | | 0.659 | hydrolase activity, acting on acid anhydrides |
| GO:0015291 | 0.291 | 0.961 | | | 0.626 | secondary active transmembrane transporter activity |
| GO:0005506 | 0.270 | 0.969 | | | 0.619 | iron ion binding |
| GO:0015405 | 0.188 | 0.998 | | | 0.593 | P-P-bond-hydrolysis-driven transmembrane transporter activity |
| GO:0004721 | 0.141 | 0.998 | | | 0.570 | phosphoprotein phosphatase activity |
| GO:0016646 | 0.138 | 0.999 | | | 0.569 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| GO:0019001 | 0.134 | 0.996 | | | 0.565 | guanyl nucleotide binding |
| GO:0005198 | 0.139 | 0.989 | | | 0.564 | structural molecule activity |