| GO:0009036 | 0.899 | 0.997 | | | 0.948 | Type II site-specific deoxyribonuclease activity |
| GO:0005337 | 0.891 | 0.999 | | | 0.945 | nucleoside transmembrane transporter activity |
| GO:0016651 | 0.837 | 0.999 | | | 0.918 | oxidoreductase activity, acting on NADH or NADPH |
| GO:0016746 | 0.818 | 0.988 | | | 0.903 | transferase activity, transferring acyl groups |
| GO:0016722 | 0.798 | 0.996 | | | 0.897 | oxidoreductase activity, oxidizing metal ions |
| GO:0016788 | 0.734 | 0.998 | | | 0.866 | hydrolase activity, acting on ester bonds |
| GO:0050485 | 0.701 | 0.999 | | | 0.850 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0047134 | 0.611 | 1.000 | | | 0.806 | protein-disulfide reductase activity |
| GO:0016772 | 0.612 | 0.999 | | | 0.805 | transferase activity, transferring phosphorus-containing groups |
| GO:0015666 | 0.540 | 0.997 | | | 0.769 | restriction endodeoxyribonuclease activity |
| GO:0015149 | 0.532 | 0.998 | | | 0.765 | hexose transmembrane transporter activity |
| GO:0004333 | 0.532 | 0.997 | | | 0.765 | fumarate hydratase activity |
| GO:0016869 | 0.540 | 0.985 | | | 0.763 | intramolecular transferase activity, transferring amino groups |
| GO:0048038 | 0.526 | 0.997 | | | 0.762 | quinone binding |
| GO:0015926 | 0.520 | 0.997 | | | 0.758 | glucosidase activity |
| GO:0015288 | 0.491 | 0.995 | | | 0.743 | porin activity |
| GO:0016888 | 0.479 | 0.999 | | | 0.739 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0005506 | 0.373 | 0.997 | | | 0.685 | iron ion binding |
| GO:0004497 | 0.339 | 0.997 | | | 0.668 | monooxygenase activity |
| GO:0031419 | 0.301 | 0.998 | | | 0.650 | cobalamin binding |