| GO:0004519 | 0.934 | 1.000 | | | 0.967 | endonuclease activity |
| GO:0015399 | 0.921 | 0.999 | | | 0.960 | primary active transmembrane transporter activity |
| GO:0005515 | 0.990 | 0.810 | | | 0.900 | protein binding |
| GO:0004540 | 0.688 | 0.995 | | | 0.842 | ribonuclease activity |
| GO:0016791 | 0.669 | 0.997 | | | 0.833 | phosphatase activity |
| GO:0016830 | 0.569 | 0.980 | | | 0.775 | carbon-carbon lyase activity |
| GO:0016817 | 0.614 | 0.921 | | | 0.767 | hydrolase activity, acting on acid anhydrides |
| GO:0016887 | 0.515 | 0.968 | | | 0.741 | ATPase activity |
| GO:0051002 | 0.465 | 0.997 | | | 0.731 | ligase activity, forming nitrogen-metal bonds |
| GO:0050485 | 0.464 | 0.993 | | | 0.729 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0046992 | 0.524 | 0.923 | | | 0.724 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0016893 | 0.550 | 0.846 | | | 0.698 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0008171 | 0.393 | 0.999 | | | 0.696 | O-methyltransferase activity |
| GO:0015075 | 0.404 | 0.982 | | | 0.693 | ion transmembrane transporter activity |
| GO:0016151 | 0.927 | 0.379 | | | 0.653 | nickel ion binding |
| GO:0050662 | 0.867 | 0.401 | | | 0.634 | coenzyme binding |
| GO:0016462 | 0.334 | 0.922 | | | 0.628 | pyrophosphatase activity |
| GO:0022890 | 0.512 | 0.701 | | | 0.606 | inorganic cation transmembrane transporter activity |
| GO:0015149 | 0.323 | 0.863 | | | 0.593 | hexose transmembrane transporter activity |
| GO:0015405 | 0.990 | 0.181 | | | 0.586 | P-P-bond-hydrolysis-driven transmembrane transporter activity |