| GO:0016730 | 1.000 | 0.999 | | | 1.000 | oxidoreductase activity, acting on iron-sulfur proteins as donors |
| GO:0050660 | 0.995 | 0.994 | | | 0.994 | FAD binding |
| GO:0050662 | 0.998 | 0.977 | | | 0.987 | coenzyme binding |
| GO:0016731 | 0.977 | 0.997 | | | 0.987 | oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor |
| GO:0009055 | 0.968 | 0.988 | | | 0.978 | electron carrier activity |
| GO:0048037 | 0.999 | 0.954 | | | 0.976 | cofactor binding |
| GO:0016491 | 0.988 | 0.923 | | | 0.956 | oxidoreductase activity |
| GO:0016705 | 0.939 | 0.040 | | | 0.490 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| GO:0016668 | 0.937 | 0.000 | | | 0.468 | oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor |
| GO:0016298 | 0.679 | 0.171 | | | 0.425 | lipase activity |
| GO:0016747 | 0.789 | 0.000 | | | 0.394 | transferase activity, transferring groups other than amino-acyl groups |
| GO:0015666 | 0.402 | 0.379 | | | 0.391 | restriction endodeoxyribonuclease activity |
| GO:0004766 | 0.740 | 0.000 | | | 0.370 | spermidine synthase activity |
| GO:0046992 | 0.524 | 0.198 | | | 0.361 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0008415 | 0.698 | 0.000 | | | 0.349 | acyltransferase activity |
| GO:0016708 | 0.000 | 0.671 | | | 0.336 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0008168 | 0.635 | 0.001 | | | 0.318 | methyltransferase activity |
| GO:0016614 | 0.626 | 0.000 | | | 0.313 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0016722 | 0.259 | 0.360 | | | 0.310 | oxidoreductase activity, oxidizing metal ions |
| GO:0016741 | 0.521 | 0.003 | | | 0.262 | transferase activity, transferring one-carbon groups |