| GO:0022884 | 1.000 | 0.999 | | | 1.000 | macromolecule transmembrane transporter activity |
| GO:0009036 | 0.989 | 0.979 | | | 0.984 | Type II site-specific deoxyribonuclease activity |
| GO:0003677 | 0.998 | 0.950 | | | 0.974 | DNA binding |
| GO:0016824 | 0.925 | 1.000 | | | 0.963 | hydrolase activity, acting on acid halide bonds |
| GO:0022892 | 0.933 | 0.972 | | | 0.953 | substrate-specific transporter activity |
| GO:0005215 | 0.931 | 0.960 | | | 0.945 | transporter activity |
| GO:0016298 | 0.979 | 0.876 | | | 0.927 | lipase activity |
| GO:0022891 | 0.824 | 0.967 | | | 0.896 | substrate-specific transmembrane transporter activity |
| GO:0016888 | 0.864 | 0.900 | | | 0.882 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0005515 | 1.000 | 0.762 | | | 0.881 | protein binding |
| GO:0005244 | 0.681 | 1.000 | | | 0.840 | voltage-gated ion channel activity |
| GO:0015666 | 0.680 | 0.984 | | | 0.832 | restriction endodeoxyribonuclease activity |
| GO:0015294 | 0.636 | 0.994 | | | 0.815 | solute:cation symporter activity |
| GO:0022804 | 0.650 | 0.976 | | | 0.813 | active transmembrane transporter activity |
| GO:0016705 | 0.627 | 0.998 | | | 0.813 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| GO:0003700 | 0.694 | 0.919 | | | 0.806 | transcription factor activity |
| GO:0004806 | 0.676 | 0.937 | | | 0.806 | triacylglycerol lipase activity |
| GO:0003916 | 0.583 | 0.998 | | | 0.791 | DNA topoisomerase activity |
| GO:0004518 | 0.995 | 0.573 | | | 0.784 | nuclease activity |
| GO:0005102 | 0.487 | 0.999 | | | 0.743 | receptor binding |