| GO:0003688 | 1.000 | 0.998 | | | 0.999 | DNA replication origin binding |
| GO:0043565 | 1.000 | 0.979 | | | 0.989 | sequence-specific DNA binding |
| GO:0003677 | 1.000 | 0.950 | | | 0.975 | DNA binding |
| GO:0017111 | 1.000 | 0.925 | | | 0.963 | nucleoside-triphosphatase activity |
| GO:0016462 | 1.000 | 0.922 | | | 0.961 | pyrophosphatase activity |
| GO:0016817 | 1.000 | 0.921 | | | 0.961 | hydrolase activity, acting on acid anhydrides |
| GO:0016818 | 0.999 | 0.919 | | | 0.959 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0008410 | 0.659 | 0.999 | | | 0.829 | CoA-transferase activity |
| GO:0005515 | 0.408 | 0.987 | | | 0.697 | protein binding |
| GO:0015666 | 0.801 | 0.379 | | | 0.590 | restriction endodeoxyribonuclease activity |
| GO:0030234 | 0.167 | 0.997 | | | 0.582 | enzyme regulator activity |
| GO:0003700 | 0.712 | 0.432 | | | 0.572 | transcription factor activity |
| GO:0016812 | 0.042 | 0.997 | | | 0.520 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| GO:0051003 | 0.765 | 0.247 | | | 0.506 | ligase activity, forming nitrogen-metal bonds, forming coordination complexes |
| GO:0051536 | 0.015 | 0.991 | | | 0.503 | iron-sulfur cluster binding |
| GO:0016741 | 0.023 | 0.977 | | | 0.500 | transferase activity, transferring one-carbon groups |
| GO:0005244 | 0.000 | 1.000 | | | 0.500 | voltage-gated ion channel activity |
| GO:0004450 | 0.000 | 0.999 | | | 0.500 | isocitrate dehydrogenase (NADP+) activity |
| GO:0016641 | 0.000 | 0.999 | | | 0.500 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor |
| GO:0003938 | 0.000 | 0.999 | | | 0.500 | IMP dehydrogenase activity |