| GO:0017111 | 1.000 | 0.925 | | | 0.963 | nucleoside-triphosphatase activity |
| GO:0016462 | 0.994 | 0.922 | | | 0.958 | pyrophosphatase activity |
| GO:0016818 | 0.997 | 0.919 | | | 0.958 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016817 | 0.972 | 0.921 | | | 0.947 | hydrolase activity, acting on acid anhydrides |
| GO:0031419 | 0.533 | 0.998 | | | 0.766 | cobalamin binding |
| GO:0030414 | 0.466 | 0.987 | | | 0.726 | protease inhibitor activity |
| GO:0001882 | 0.395 | 0.998 | | | 0.696 | nucleoside binding |
| GO:0003700 | 0.415 | 0.975 | | | 0.695 | transcription factor activity |
| GO:0003677 | 0.435 | 0.950 | | | 0.692 | DNA binding |
| GO:0015082 | 0.326 | 0.995 | | | 0.661 | di-, tri-valent inorganic cation transmembrane transporter activity |
| GO:0050897 | 0.209 | 0.997 | | | 0.603 | cobalt ion binding |
| GO:0015294 | 0.207 | 0.994 | | | 0.600 | solute:cation symporter activity |
| GO:0015293 | 0.189 | 0.996 | | | 0.592 | symporter activity |
| GO:0016798 | 0.167 | 0.999 | | | 0.583 | hydrolase activity, acting on glycosyl bonds |
| GO:0004300 | 0.088 | 0.998 | | | 0.543 | enoyl-CoA hydratase activity |
| GO:0046906 | 0.089 | 0.993 | | | 0.541 | tetrapyrrole binding |
| GO:0010181 | 0.086 | 0.995 | | | 0.541 | FMN binding |
| GO:0000155 | 0.084 | 0.994 | | | 0.539 | two-component sensor activity |
| GO:0004872 | 0.081 | 0.996 | | | 0.538 | receptor activity |
| GO:0016812 | 0.063 | 0.997 | | | 0.530 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |