| GO:0003700 | 0.961 | 0.975 | | | 0.968 | transcription factor activity |
| GO:0016824 | 0.879 | 1.000 | | | 0.940 | hydrolase activity, acting on acid halide bonds |
| GO:0016407 | 0.457 | 0.986 | | | 0.721 | acetyltransferase activity |
| GO:0046857 | 0.382 | 0.999 | | | 0.690 | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| GO:0015116 | 0.291 | 1.000 | | | 0.645 | sulfate transmembrane transporter activity |
| GO:0046915 | 0.196 | 0.998 | | | 0.597 | transition metal ion transmembrane transporter activity |
| GO:0015419 | 0.191 | 0.995 | | | 0.593 | sulfate transmembrane-transporting ATPase activity |
| GO:0008234 | 0.186 | 0.998 | | | 0.592 | cysteine-type peptidase activity |
| GO:0017153 | 0.182 | 0.999 | | | 0.591 | sodium:dicarboxylate symporter activity |
| GO:0003677 | 0.197 | 0.950 | | | 0.573 | DNA binding |
| GO:0070011 | 0.147 | 0.997 | | | 0.572 | peptidase activity, acting on L-amino acid peptides |
| GO:0004252 | 0.116 | 0.999 | | | 0.557 | serine-type endopeptidase activity |
| GO:0009008 | 0.108 | 0.997 | | | 0.552 | DNA-methyltransferase activity |
| GO:0004518 | 0.101 | 0.996 | | | 0.549 | nuclease activity |
| GO:0008080 | 0.572 | 0.500 | | | 0.536 | N-acetyltransferase activity |
| GO:0016811 | 0.060 | 0.996 | | | 0.528 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| GO:0015291 | 0.094 | 0.961 | | | 0.527 | secondary active transmembrane transporter activity |
| GO:0016747 | 0.057 | 0.993 | | | 0.525 | transferase activity, transferring groups other than amino-acyl groups |
| GO:0016869 | 0.061 | 0.985 | | | 0.523 | intramolecular transferase activity, transferring amino groups |
| GO:0008236 | 0.036 | 0.998 | | | 0.517 | serine-type peptidase activity |