| GO:0003916 | 1.000 | 0.998 | | | 0.999 | DNA topoisomerase activity |
| GO:0019213 | 0.993 | 0.998 | | | 0.996 | deacetylase activity |
| GO:0016853 | 1.000 | 0.936 | | | 0.968 | isomerase activity |
| GO:0046992 | 0.945 | 0.985 | | | 0.965 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0015149 | 0.709 | 0.947 | | | 0.828 | hexose transmembrane transporter activity |
| GO:0004520 | 0.819 | 0.621 | | | 0.720 | endodeoxyribonuclease activity |
| GO:0005515 | 0.893 | 0.538 | | | 0.715 | protein binding |
| GO:0005509 | 0.872 | 0.529 | | | 0.700 | calcium ion binding |
| GO:0009036 | 0.995 | 0.405 | | | 0.700 | Type II site-specific deoxyribonuclease activity |
| GO:0015666 | 1.000 | 0.379 | | | 0.689 | restriction endodeoxyribonuclease activity |
| GO:0009055 | 0.376 | 0.996 | | | 0.686 | electron carrier activity |
| GO:0017171 | 0.997 | 0.297 | | | 0.647 | serine hydrolase activity |
| GO:0004536 | 0.720 | 0.571 | | | 0.645 | deoxyribonuclease activity |
| GO:0003700 | 0.840 | 0.377 | | | 0.608 | transcription factor activity |
| GO:0016861 | 0.216 | 0.999 | | | 0.608 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| GO:0016702 | 0.902 | 0.295 | | | 0.598 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| GO:0016868 | 0.158 | 0.998 | | | 0.578 | intramolecular transferase activity, phosphotransferases |
| GO:0016701 | 0.594 | 0.562 | | | 0.578 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen |
| GO:0005102 | 0.157 | 0.988 | | | 0.573 | receptor binding |
| GO:0005402 | 0.827 | 0.312 | | | 0.570 | cation:sugar symporter activity |