| GO:0016987 | 1.000 | 0.998 | | | 0.999 | sigma factor activity |
| GO:0016986 | 1.000 | 0.998 | | | 0.999 | transcription initiation factor activity |
| GO:0003700 | 1.000 | 0.996 | | | 0.998 | transcription factor activity |
| GO:0030528 | 0.999 | 0.992 | | | 0.995 | transcription regulator activity |
| GO:0003677 | 0.995 | 0.950 | | | 0.972 | DNA binding |
| GO:0015666 | 0.966 | 0.379 | | | 0.673 | restriction endodeoxyribonuclease activity |
| GO:0016722 | 0.804 | 0.360 | | | 0.582 | oxidoreductase activity, oxidizing metal ions |
| GO:0046870 | 0.847 | 0.219 | | | 0.533 | cadmium ion binding |
| GO:0005515 | 0.993 | 0.067 | | | 0.530 | protein binding |
| GO:0046857 | 0.967 | 0.000 | | | 0.484 | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| GO:0060089 | 0.950 | 0.007 | | | 0.478 | molecular transducer activity |
| GO:0004518 | 0.937 | 0.002 | | | 0.469 | nuclease activity |
| GO:0009036 | 0.479 | 0.405 | | | 0.442 | Type II site-specific deoxyribonuclease activity |
| GO:0016651 | 0.877 | 0.000 | | | 0.439 | oxidoreductase activity, acting on NADH or NADPH |
| GO:0004721 | 0.873 | 0.000 | | | 0.436 | phosphoprotein phosphatase activity |
| GO:0022892 | 0.853 | 0.001 | | | 0.427 | substrate-specific transporter activity |
| GO:0047134 | 0.849 | 0.000 | | | 0.424 | protein-disulfide reductase activity |
| GO:0016798 | 0.828 | 0.005 | | | 0.417 | hydrolase activity, acting on glycosyl bonds |
| GO:0004872 | 0.769 | 0.059 | | | 0.414 | receptor activity |
| GO:0004871 | 0.807 | 0.007 | | | 0.407 | signal transducer activity |