| GO:0015399 | 0.971 | 0.992 | | | 0.981 | primary active transmembrane transporter activity |
| GO:0000156 | 0.911 | 0.999 | | | 0.955 | two-component response regulator activity |
| GO:0016887 | 0.852 | 0.968 | | | 0.910 | ATPase activity |
| GO:0017171 | 0.891 | 0.912 | | | 0.902 | serine hydrolase activity |
| GO:0003700 | 0.981 | 0.736 | | | 0.858 | transcription factor activity |
| GO:0005515 | 1.000 | 0.692 | | | 0.846 | protein binding |
| GO:0004497 | 0.733 | 0.927 | | | 0.830 | monooxygenase activity |
| GO:0016817 | 0.726 | 0.921 | | | 0.824 | hydrolase activity, acting on acid anhydrides |
| GO:0015144 | 0.778 | 0.868 | | | 0.823 | carbohydrate transmembrane transporter activity |
| GO:0050485 | 0.663 | 0.980 | | | 0.822 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0015926 | 0.625 | 0.953 | | | 0.789 | glucosidase activity |
| GO:0051002 | 0.630 | 0.921 | | | 0.776 | ligase activity, forming nitrogen-metal bonds |
| GO:0004872 | 0.737 | 0.814 | | | 0.775 | receptor activity |
| GO:0003899 | 0.740 | 0.795 | | | 0.768 | DNA-directed RNA polymerase activity |
| GO:0046873 | 0.538 | 0.995 | | | 0.767 | metal ion transmembrane transporter activity |
| GO:0016893 | 0.533 | 0.996 | | | 0.765 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0016818 | 0.607 | 0.919 | | | 0.763 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016462 | 0.584 | 0.922 | | | 0.753 | pyrophosphatase activity |
| GO:0051003 | 0.539 | 0.943 | | | 0.741 | ligase activity, forming nitrogen-metal bonds, forming coordination complexes |
| GO:0042802 | 0.623 | 0.841 | | | 0.732 | identical protein binding |