| GO:0008168 | 0.987 | 0.979 | | | 0.983 | methyltransferase activity |
| GO:0016741 | 0.892 | 0.977 | | | 0.935 | transferase activity, transferring one-carbon groups |
| GO:0008175 | 0.484 | 0.997 | | | 0.741 | tRNA methyltransferase activity |
| GO:0008757 | 0.358 | 0.984 | | | 0.671 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0015666 | 0.788 | 0.379 | | | 0.584 | restriction endodeoxyribonuclease activity |
| GO:0009036 | 0.698 | 0.405 | | | 0.551 | Type II site-specific deoxyribonuclease activity |
| GO:0004497 | 0.940 | 0.107 | | | 0.524 | monooxygenase activity |
| GO:0016423 | 0.040 | 0.997 | | | 0.519 | tRNA (guanine) methyltransferase activity |
| GO:0030798 | 0.000 | 0.999 | | | 0.500 | trans-aconitate 2-methyltransferase activity |
| GO:0016300 | 0.000 | 0.997 | | | 0.499 | tRNA (uracil) methyltransferase activity |
| GO:0005375 | 0.000 | 0.993 | | | 0.496 | copper ion transmembrane transporter activity |
| GO:0051920 | 0.000 | 0.991 | | | 0.496 | peroxiredoxin activity |
| GO:0008172 | 0.942 | 0.005 | | | 0.473 | S-methyltransferase activity |
| GO:0016788 | 0.847 | 0.004 | | | 0.425 | hydrolase activity, acting on ester bonds |
| GO:0004867 | 0.650 | 0.152 | | | 0.401 | serine-type endopeptidase inhibitor activity |
| GO:0016491 | 0.785 | 0.001 | | | 0.393 | oxidoreductase activity |
| GO:0009008 | 0.666 | 0.109 | | | 0.387 | DNA-methyltransferase activity |
| GO:0008170 | 0.756 | 0.000 | | | 0.378 | N-methyltransferase activity |
| GO:0051002 | 0.466 | 0.248 | | | 0.357 | ligase activity, forming nitrogen-metal bonds |
| GO:0000179 | 0.000 | 0.692 | | | 0.346 | rRNA (adenine-N6,N6-)-dimethyltransferase activity |