| GO:0009008 | 0.925 | 0.997 | | | 0.961 | DNA-methyltransferase activity |
| GO:0004872 | 0.838 | 0.745 | | | 0.791 | receptor activity |
| GO:0009036 | 0.965 | 0.405 | | | 0.685 | Type II site-specific deoxyribonuclease activity |
| GO:0008757 | 0.364 | 0.984 | | | 0.674 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0016741 | 0.305 | 0.977 | | | 0.641 | transferase activity, transferring one-carbon groups |
| GO:0046992 | 0.310 | 0.961 | | | 0.635 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0015666 | 0.862 | 0.379 | | | 0.621 | restriction endodeoxyribonuclease activity |
| GO:0008430 | 0.526 | 0.624 | | | 0.575 | selenium binding |
| GO:0016298 | 0.963 | 0.171 | | | 0.567 | lipase activity |
| GO:0042578 | 0.994 | 0.065 | | | 0.529 | phosphoric ester hydrolase activity |
| GO:0008168 | 0.074 | 0.979 | | | 0.527 | methyltransferase activity |
| GO:0004401 | 1.000 | 0.000 | | | 0.500 | histidinol-phosphatase activity |
| GO:0009007 | 0.000 | 0.997 | | | 0.499 | site-specific DNA-methyltransferase (adenine-specific) activity |
| GO:0004175 | 0.995 | 0.000 | | | 0.497 | endopeptidase activity |
| GO:0003700 | 0.003 | 0.975 | | | 0.489 | transcription factor activity |
| GO:0016708 | 0.874 | 0.104 | | | 0.489 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0031419 | 0.229 | 0.724 | | | 0.477 | cobalamin binding |
| GO:0004725 | 0.946 | 0.000 | | | 0.473 | protein tyrosine phosphatase activity |
| GO:0008233 | 0.907 | 0.027 | | | 0.467 | peptidase activity |
| GO:0070011 | 0.926 | 0.000 | | | 0.463 | peptidase activity, acting on L-amino acid peptides |