| GO:0003887 | 0.989 | 0.996 | | | 0.992 | DNA-directed DNA polymerase activity |
| GO:0016772 | 0.867 | 0.931 | | | 0.899 | transferase activity, transferring phosphorus-containing groups |
| GO:0016741 | 0.810 | 0.977 | | | 0.894 | transferase activity, transferring one-carbon groups |
| GO:0016462 | 0.854 | 0.922 | | | 0.888 | pyrophosphatase activity |
| GO:0034061 | 0.975 | 0.795 | | | 0.885 | DNA polymerase activity |
| GO:0000287 | 0.790 | 0.956 | | | 0.873 | magnesium ion binding |
| GO:0008168 | 0.723 | 0.979 | | | 0.851 | methyltransferase activity |
| GO:0004536 | 0.688 | 0.995 | | | 0.841 | deoxyribonuclease activity |
| GO:0030528 | 0.643 | 0.992 | | | 0.817 | transcription regulator activity |
| GO:0016298 | 0.723 | 0.815 | | | 0.769 | lipase activity |
| GO:0015103 | 0.488 | 0.998 | | | 0.743 | inorganic anion transmembrane transporter activity |
| GO:0042802 | 0.465 | 0.998 | | | 0.731 | identical protein binding |
| GO:0016779 | 0.461 | 0.970 | | | 0.716 | nucleotidyltransferase activity |
| GO:0004497 | 0.890 | 0.531 | | | 0.711 | monooxygenase activity |
| GO:0016874 | 0.458 | 0.921 | | | 0.690 | ligase activity |
| GO:0016791 | 0.352 | 0.997 | | | 0.675 | phosphatase activity |
| GO:0008170 | 0.276 | 0.998 | | | 0.637 | N-methyltransferase activity |
| GO:0004871 | 0.209 | 0.995 | | | 0.602 | signal transducer activity |
| GO:0015666 | 0.823 | 0.379 | | | 0.601 | restriction endodeoxyribonuclease activity |
| GO:0016645 | 0.149 | 0.996 | | | 0.573 | oxidoreductase activity, acting on the CH-NH group of donors |