| GO:0015666 | 0.999 | 0.997 | | | 0.998 | restriction endodeoxyribonuclease activity |
| GO:0046992 | 0.556 | 0.923 | | | 0.740 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0051002 | 0.381 | 0.997 | | | 0.689 | ligase activity, forming nitrogen-metal bonds |
| GO:0048037 | 0.263 | 0.999 | | | 0.631 | cofactor binding |
| GO:0016772 | 0.751 | 0.405 | | | 0.578 | transferase activity, transferring phosphorus-containing groups |
| GO:0008483 | 0.098 | 0.991 | | | 0.545 | transaminase activity |
| GO:0000287 | 0.119 | 0.956 | | | 0.537 | magnesium ion binding |
| GO:0004486 | 1.000 | 0.063 | | | 0.532 | methylenetetrahydrofolate dehydrogenase activity |
| GO:0016462 | 0.116 | 0.922 | | | 0.519 | pyrophosphatase activity |
| GO:0016705 | 0.039 | 0.997 | | | 0.518 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| GO:0016811 | 0.036 | 0.995 | | | 0.516 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| GO:0046912 | 0.043 | 0.984 | | | 0.513 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
| GO:0016779 | 0.026 | 0.996 | | | 0.511 | nucleotidyltransferase activity |
| GO:0022892 | 0.018 | 0.999 | | | 0.509 | substrate-specific transporter activity |
| GO:0016835 | 0.010 | 0.998 | | | 0.504 | carbon-oxygen lyase activity |
| GO:0016645 | 1.000 | 0.005 | | | 0.503 | oxidoreductase activity, acting on the CH-NH group of donors |
| GO:0016830 | 0.005 | 0.998 | | | 0.502 | carbon-carbon lyase activity |
| GO:0004519 | 0.003 | 1.000 | | | 0.501 | endonuclease activity |
| GO:0004477 | 1.000 | 0.000 | | | 0.500 | methenyltetrahydrofolate cyclohydrolase activity |
| GO:0004349 | 0.000 | 1.000 | | | 0.500 | glutamate 5-kinase activity |