| GO:0003899 | 1.000 | 0.995 | | | 0.997 | DNA-directed RNA polymerase activity |
| GO:0034062 | 1.000 | 0.990 | | | 0.995 | RNA polymerase activity |
| GO:0003677 | 0.948 | 0.950 | | | 0.949 | DNA binding |
| GO:0016779 | 0.917 | 0.970 | | | 0.944 | nucleotidyltransferase activity |
| GO:0016298 | 0.800 | 0.873 | | | 0.836 | lipase activity |
| GO:0015666 | 0.630 | 0.963 | | | 0.796 | restriction endodeoxyribonuclease activity |
| GO:0004806 | 0.636 | 0.935 | | | 0.785 | triacylglycerol lipase activity |
| GO:0016772 | 0.637 | 0.931 | | | 0.784 | transferase activity, transferring phosphorus-containing groups |
| GO:0004520 | 0.792 | 0.652 | | | 0.722 | endodeoxyribonuclease activity |
| GO:0009036 | 0.952 | 0.405 | | | 0.678 | Type II site-specific deoxyribonuclease activity |
| GO:0016722 | 0.940 | 0.360 | | | 0.650 | oxidoreductase activity, oxidizing metal ions |
| GO:0005509 | 0.408 | 0.880 | | | 0.644 | calcium ion binding |
| GO:0016788 | 0.915 | 0.328 | | | 0.622 | hydrolase activity, acting on ester bonds |
| GO:0005507 | 0.274 | 0.879 | | | 0.576 | copper ion binding |
| GO:0046992 | 0.907 | 0.198 | | | 0.553 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0005337 | 0.823 | 0.248 | | | 0.535 | nucleoside transmembrane transporter activity |
| GO:0019200 | 0.082 | 0.988 | | | 0.535 | carbohydrate kinase activity |
| GO:0051002 | 0.803 | 0.248 | | | 0.525 | ligase activity, forming nitrogen-metal bonds |
| GO:0016888 | 0.876 | 0.152 | | | 0.514 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0016893 | 0.978 | 0.032 | | | 0.505 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |