| GO:0042578 | 1.000 | 0.997 | | | 0.998 | phosphoric ester hydrolase activity |
| GO:0008252 | 0.972 | 0.988 | | | 0.980 | nucleotidase activity |
| GO:0016722 | 0.815 | 0.999 | | | 0.907 | oxidoreductase activity, oxidizing metal ions |
| GO:0016835 | 0.763 | 0.984 | | | 0.874 | carbon-oxygen lyase activity |
| GO:0005515 | 0.730 | 0.987 | | | 0.858 | protein binding |
| GO:0016788 | 0.740 | 0.967 | | | 0.854 | hydrolase activity, acting on ester bonds |
| GO:0016829 | 0.751 | 0.953 | | | 0.852 | lyase activity |
| GO:0004871 | 0.597 | 0.995 | | | 0.796 | signal transducer activity |
| GO:0009036 | 0.574 | 0.989 | | | 0.781 | Type II site-specific deoxyribonuclease activity |
| GO:0004437 | 0.500 | 0.998 | | | 0.749 | inositol or phosphatidylinositol phosphatase activity |
| GO:0032561 | 0.495 | 0.999 | | | 0.747 | guanyl ribonucleotide binding |
| GO:0000287 | 0.435 | 0.956 | | | 0.695 | magnesium ion binding |
| GO:0048037 | 0.354 | 0.954 | | | 0.654 | cofactor binding |
| GO:0016652 | 0.270 | 0.998 | | | 0.634 | oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor |
| GO:0003700 | 0.279 | 0.975 | | | 0.627 | transcription factor activity |
| GO:0016836 | 0.256 | 0.980 | | | 0.618 | hydro-lyase activity |
| GO:0019213 | 0.192 | 0.998 | | | 0.595 | deacetylase activity |
| GO:0005525 | 0.209 | 0.980 | | | 0.594 | GTP binding |
| GO:0004527 | 0.106 | 0.996 | | | 0.551 | exonuclease activity |
| GO:0030234 | 0.079 | 0.997 | | | 0.538 | enzyme regulator activity |