| GO:0050485 | 0.906 | 0.999 | | | 0.952 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0016788 | 0.911 | 0.967 | | | 0.939 | hydrolase activity, acting on ester bonds |
| GO:0009036 | 0.991 | 0.405 | | | 0.698 | Type II site-specific deoxyribonuclease activity |
| GO:0003774 | 0.238 | 0.998 | | | 0.618 | motor activity |
| GO:0016874 | 0.202 | 0.921 | | | 0.562 | ligase activity |
| GO:0004872 | 0.110 | 0.996 | | | 0.553 | receptor activity |
| GO:0016841 | 0.600 | 0.500 | | | 0.550 | ammonia-lyase activity |
| GO:0004536 | 0.092 | 0.995 | | | 0.543 | deoxyribonuclease activity |
| GO:0008236 | 0.084 | 0.998 | | | 0.541 | serine-type peptidase activity |
| GO:0016859 | 0.071 | 0.996 | | | 0.534 | cis-trans isomerase activity |
| GO:0031420 | 0.067 | 0.998 | | | 0.532 | alkali metal ion binding |
| GO:0042625 | 0.058 | 0.994 | | | 0.526 | ATPase activity, coupled to transmembrane movement of ions |
| GO:0004300 | 0.044 | 0.999 | | | 0.522 | enoyl-CoA hydratase activity |
| GO:0008415 | 0.052 | 0.990 | | | 0.521 | acyltransferase activity |
| GO:0022838 | 0.035 | 0.996 | | | 0.516 | substrate specific channel activity |
| GO:0004520 | 0.038 | 0.992 | | | 0.515 | endodeoxyribonuclease activity |
| GO:0016879 | 0.047 | 0.979 | | | 0.513 | ligase activity, forming carbon-nitrogen bonds |
| GO:0015082 | 0.027 | 0.995 | | | 0.511 | di-, tri-valent inorganic cation transmembrane transporter activity |
| GO:0000156 | 0.022 | 0.999 | | | 0.511 | two-component response regulator activity |
| GO:0016878 | 0.023 | 0.998 | | | 0.510 | acid-thiol ligase activity |