| GO:0019825 | 0.987 | 0.965 | | | 0.976 | oxygen binding |
| GO:0016831 | 0.715 | 0.986 | | | 0.851 | carboxy-lyase activity |
| GO:0004620 | 0.451 | 0.997 | | | 0.724 | phospholipase activity |
| GO:0016854 | 0.441 | 0.996 | | | 0.718 | racemase and epimerase activity |
| GO:0016298 | 0.362 | 0.997 | | | 0.679 | lipase activity |
| GO:0008233 | 0.309 | 0.867 | | | 0.588 | peptidase activity |
| GO:0015662 | 0.172 | 0.996 | | | 0.584 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism |
| GO:0015419 | 0.167 | 0.995 | | | 0.581 | sulfate transmembrane-transporting ATPase activity |
| GO:0009008 | 0.283 | 0.860 | | | 0.572 | DNA-methyltransferase activity |
| GO:0008235 | 0.345 | 0.769 | | | 0.557 | metalloexopeptidase activity |
| GO:0016769 | 0.110 | 0.989 | | | 0.550 | transferase activity, transferring nitrogenous groups |
| GO:0016788 | 0.102 | 0.967 | | | 0.535 | hydrolase activity, acting on ester bonds |
| GO:0016741 | 0.088 | 0.977 | | | 0.533 | transferase activity, transferring one-carbon groups |
| GO:0016855 | 0.065 | 0.998 | | | 0.532 | racemase and epimerase activity, acting on amino acids and derivatives |
| GO:0016701 | 0.064 | 0.999 | | | 0.531 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen |
| GO:0015926 | 0.141 | 0.917 | | | 0.529 | glucosidase activity |
| GO:0016791 | 0.056 | 0.997 | | | 0.527 | phosphatase activity |
| GO:0016879 | 0.072 | 0.979 | | | 0.526 | ligase activity, forming carbon-nitrogen bonds |
| GO:0008234 | 0.046 | 0.999 | | | 0.522 | cysteine-type peptidase activity |
| GO:0016893 | 0.045 | 0.996 | | | 0.521 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |