| GO:0004871 | 1.000 | 0.995 | | | 0.998 | signal transducer activity |
| GO:0060089 | 1.000 | 0.989 | | | 0.994 | molecular transducer activity |
| GO:0016775 | 0.843 | 0.995 | | | 0.919 | phosphotransferase activity, nitrogenous group as acceptor |
| GO:0030528 | 0.991 | 0.760 | | | 0.875 | transcription regulator activity |
| GO:0016301 | 0.764 | 0.975 | | | 0.870 | kinase activity |
| GO:0016772 | 0.751 | 0.931 | | | 0.841 | transferase activity, transferring phosphorus-containing groups |
| GO:0008238 | 0.657 | 0.997 | | | 0.827 | exopeptidase activity |
| GO:0046992 | 0.653 | 0.999 | | | 0.826 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0003677 | 0.594 | 0.950 | | | 0.772 | DNA binding |
| GO:0019001 | 0.579 | 0.833 | | | 0.706 | guanyl nucleotide binding |
| GO:0000155 | 0.344 | 0.994 | | | 0.669 | two-component sensor activity |
| GO:0004672 | 0.338 | 0.992 | | | 0.665 | protein kinase activity |
| GO:0004673 | 0.332 | 0.996 | | | 0.664 | protein histidine kinase activity |
| GO:0016857 | 0.277 | 0.996 | | | 0.636 | racemase and epimerase activity, acting on carbohydrates and derivatives |
| GO:0031402 | 0.277 | 0.996 | | | 0.636 | sodium ion binding |
| GO:0004620 | 0.242 | 0.997 | | | 0.620 | phospholipase activity |
| GO:0015926 | 0.154 | 0.997 | | | 0.576 | glucosidase activity |
| GO:0030234 | 0.111 | 0.997 | | | 0.554 | enzyme regulator activity |
| GO:0005402 | 0.103 | 0.994 | | | 0.548 | cation:sugar symporter activity |
| GO:0046912 | 0.092 | 0.997 | | | 0.545 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |