| GO:0004808 | 1.000 | 0.996 | | | 0.998 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity |
| GO:0000049 | 1.000 | 0.995 | | | 0.998 | tRNA binding |
| GO:0008757 | 1.000 | 0.984 | | | 0.992 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0008168 | 1.000 | 0.979 | | | 0.990 | methyltransferase activity |
| GO:0016741 | 1.000 | 0.977 | | | 0.989 | transferase activity, transferring one-carbon groups |
| GO:0008175 | 1.000 | 0.000 | | | 0.500 | tRNA methyltransferase activity |
| GO:0008173 | 1.000 | 0.000 | | | 0.500 | RNA methyltransferase activity |
| GO:0004791 | 0.000 | 0.999 | | | 0.500 | thioredoxin-disulfide reductase activity |
| GO:0004459 | 0.000 | 0.997 | | | 0.499 | L-lactate dehydrogenase activity |
| GO:0005375 | 0.000 | 0.993 | | | 0.496 | copper ion transmembrane transporter activity |
| GO:0051920 | 0.000 | 0.991 | | | 0.496 | peroxiredoxin activity |
| GO:0015077 | 0.000 | 0.990 | | | 0.495 | monovalent inorganic cation transmembrane transporter activity |
| GO:0016805 | 0.906 | 0.000 | | | 0.453 | dipeptidase activity |
| GO:0009036 | 0.444 | 0.405 | | | 0.425 | Type II site-specific deoxyribonuclease activity |
| GO:0004175 | 0.831 | 0.000 | | | 0.415 | endopeptidase activity |
| GO:0015666 | 0.407 | 0.379 | | | 0.393 | restriction endodeoxyribonuclease activity |
| GO:0008237 | 0.752 | 0.004 | | | 0.378 | metallopeptidase activity |
| GO:0016726 | 0.658 | 0.034 | | | 0.346 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor |
| GO:0016722 | 0.656 | 0.000 | | | 0.328 | oxidoreductase activity, oxidizing metal ions |
| GO:0051002 | 0.385 | 0.248 | | | 0.316 | ligase activity, forming nitrogen-metal bonds |