| GO:0015297 | 1.000 | 0.998 | | | 0.999 | antiporter activity |
| GO:0015932 | 0.976 | 0.998 | | | 0.987 | nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity |
| GO:0015075 | 0.987 | 0.982 | | | 0.984 | ion transmembrane transporter activity |
| GO:0008324 | 0.989 | 0.961 | | | 0.975 | cation transmembrane transporter activity |
| GO:0015925 | 0.908 | 0.989 | | | 0.949 | galactosidase activity |
| GO:0031420 | 0.884 | 0.998 | | | 0.941 | alkali metal ion binding |
| GO:0015300 | 0.840 | 0.993 | | | 0.917 | solute:solute antiporter activity |
| GO:0008081 | 0.833 | 0.998 | | | 0.915 | phosphoric diester hydrolase activity |
| GO:0015419 | 0.411 | 0.995 | | | 0.703 | sulfate transmembrane-transporting ATPase activity |
| GO:0015149 | 0.873 | 0.500 | | | 0.686 | hexose transmembrane transporter activity |
| GO:0015296 | 0.370 | 1.000 | | | 0.685 | anion:cation symporter activity |
| GO:0004888 | 0.782 | 0.500 | | | 0.641 | transmembrane receptor activity |
| GO:0016645 | 0.278 | 0.954 | | | 0.616 | oxidoreductase activity, acting on the CH-NH group of donors |
| GO:0016893 | 0.208 | 0.998 | | | 0.603 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0022892 | 0.997 | 0.152 | | | 0.575 | substrate-specific transporter activity |
| GO:0010181 | 0.143 | 0.995 | | | 0.569 | FMN binding |
| GO:0005216 | 0.827 | 0.247 | | | 0.537 | ion channel activity |
| GO:0005402 | 0.105 | 0.961 | | | 0.533 | cation:sugar symporter activity |
| GO:0005337 | 0.675 | 0.383 | | | 0.529 | nucleoside transmembrane transporter activity |
| GO:0016887 | 0.058 | 0.995 | | | 0.526 | ATPase activity |