| GO:0004659 | 1.000 | 0.999 | | | 1.000 | prenyltransferase activity |
| GO:0030528 | 0.962 | 1.000 | | | 0.981 | transcription regulator activity |
| GO:0016757 | 0.601 | 0.995 | | | 0.798 | transferase activity, transferring glycosyl groups |
| GO:0001882 | 0.593 | 0.997 | | | 0.795 | nucleoside binding |
| GO:0016799 | 0.563 | 0.997 | | | 0.780 | hydrolase activity, hydrolyzing N-glycosyl compounds |
| GO:0015294 | 0.504 | 0.996 | | | 0.750 | solute:cation symporter activity |
| GO:0009036 | 0.449 | 0.997 | | | 0.723 | Type II site-specific deoxyribonuclease activity |
| GO:0004871 | 0.415 | 0.995 | | | 0.705 | signal transducer activity |
| GO:0016708 | 0.349 | 0.998 | | | 0.674 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor |
| GO:0015075 | 0.358 | 0.982 | | | 0.670 | ion transmembrane transporter activity |
| GO:0016772 | 0.893 | 0.405 | | | 0.649 | transferase activity, transferring phosphorus-containing groups |
| GO:0015666 | 0.244 | 0.997 | | | 0.621 | restriction endodeoxyribonuclease activity |
| GO:0043565 | 0.213 | 0.967 | | | 0.590 | sequence-specific DNA binding |
| GO:0016866 | 0.170 | 0.996 | | | 0.583 | intramolecular transferase activity |
| GO:0015295 | 0.160 | 0.997 | | | 0.579 | solute:hydrogen symporter activity |
| GO:0017153 | 0.160 | 0.987 | | | 0.573 | sodium:dicarboxylate symporter activity |
| GO:0005351 | 0.121 | 0.997 | | | 0.559 | sugar:hydrogen symporter activity |
| GO:0005216 | 0.846 | 0.247 | | | 0.546 | ion channel activity |
| GO:0003774 | 0.094 | 0.998 | | | 0.546 | motor activity |
| GO:0016491 | 0.090 | 0.998 | | | 0.544 | oxidoreductase activity |