| GO:0004222 | 1.000 | 1.000 | | | 1.000 | metalloendopeptidase activity |
| GO:0004175 | 1.000 | 0.993 | | | 0.996 | endopeptidase activity |
| GO:0008270 | 0.994 | 0.949 | | | 0.972 | zinc ion binding |
| GO:0015077 | 0.873 | 0.990 | | | 0.931 | monovalent inorganic cation transmembrane transporter activity |
| GO:0016722 | 0.609 | 0.996 | | | 0.803 | oxidoreductase activity, oxidizing metal ions |
| GO:0016903 | 0.492 | 0.998 | | | 0.745 | oxidoreductase activity, acting on the aldehyde or oxo group of donors |
| GO:0009008 | 0.493 | 0.997 | | | 0.745 | DNA-methyltransferase activity |
| GO:0004872 | 0.449 | 0.996 | | | 0.722 | receptor activity |
| GO:0004673 | 0.406 | 0.996 | | | 0.701 | protein histidine kinase activity |
| GO:0009036 | 0.949 | 0.405 | | | 0.677 | Type II site-specific deoxyribonuclease activity |
| GO:0016620 | 0.269 | 0.996 | | | 0.632 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| GO:0004672 | 0.248 | 0.992 | | | 0.620 | protein kinase activity |
| GO:0046915 | 0.202 | 0.998 | | | 0.600 | transition metal ion transmembrane transporter activity |
| GO:0050660 | 0.194 | 0.999 | | | 0.596 | FAD binding |
| GO:0016830 | 0.171 | 0.980 | | | 0.576 | carbon-carbon lyase activity |
| GO:0003700 | 0.173 | 0.975 | | | 0.574 | transcription factor activity |
| GO:0000287 | 0.181 | 0.956 | | | 0.568 | magnesium ion binding |
| GO:0015075 | 0.119 | 0.982 | | | 0.550 | ion transmembrane transporter activity |
| GO:0016829 | 0.847 | 0.244 | | | 0.546 | lyase activity |
| GO:0016810 | 0.089 | 0.992 | | | 0.540 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |