| GO:0009036 | 0.999 | 0.995 | | | 0.997 | Type II site-specific deoxyribonuclease activity |
| GO:0016773 | 0.879 | 0.984 | | | 0.931 | phosphotransferase activity, alcohol group as acceptor |
| GO:0015149 | 0.896 | 0.868 | | | 0.882 | hexose transmembrane transporter activity |
| GO:0004872 | 0.954 | 0.778 | | | 0.866 | receptor activity |
| GO:0016563 | 0.912 | 0.771 | | | 0.842 | transcription activator activity |
| GO:0005216 | 0.827 | 0.747 | | | 0.787 | ion channel activity |
| GO:0016811 | 0.878 | 0.612 | | | 0.745 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| GO:0030234 | 0.849 | 0.629 | | | 0.739 | enzyme regulator activity |
| GO:0008757 | 0.477 | 0.984 | | | 0.731 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0016772 | 0.476 | 0.931 | | | 0.703 | transferase activity, transferring phosphorus-containing groups |
| GO:0016879 | 0.380 | 0.979 | | | 0.680 | ligase activity, forming carbon-nitrogen bonds |
| GO:0003700 | 0.877 | 0.461 | | | 0.669 | transcription factor activity |
| GO:0004725 | 0.382 | 0.946 | | | 0.664 | protein tyrosine phosphatase activity |
| GO:0015666 | 0.940 | 0.379 | | | 0.659 | restriction endodeoxyribonuclease activity |
| GO:0016639 | 0.510 | 0.794 | | | 0.652 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| GO:0016433 | 0.832 | 0.461 | | | 0.647 | rRNA (adenine) methyltransferase activity |
| GO:0004396 | 0.646 | 0.623 | | | 0.634 | hexokinase activity |
| GO:0016853 | 0.360 | 0.902 | | | 0.631 | isomerase activity |
| GO:0016652 | 0.250 | 0.997 | | | 0.624 | oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor |
| GO:0019001 | 1.000 | 0.247 | | | 0.624 | guanyl nucleotide binding |