| GO:0008907 | 0.898 | 1.000 | | | 0.949 | integrase activity |
| GO:0003995 | 0.806 | 0.998 | | | 0.902 | acyl-CoA dehydrogenase activity |
| GO:0016151 | 0.713 | 0.991 | | | 0.852 | nickel ion binding |
| GO:0004857 | 0.687 | 0.999 | | | 0.843 | enzyme inhibitor activity |
| GO:0005337 | 0.673 | 0.999 | | | 0.836 | nucleoside transmembrane transporter activity |
| GO:0003700 | 0.513 | 0.975 | | | 0.744 | transcription factor activity |
| GO:0009036 | 0.489 | 0.999 | | | 0.744 | Type II site-specific deoxyribonuclease activity |
| GO:0051002 | 0.521 | 0.933 | | | 0.727 | ligase activity, forming nitrogen-metal bonds |
| GO:0050485 | 0.496 | 0.951 | | | 0.723 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor |
| GO:0042623 | 0.435 | 0.994 | | | 0.714 | ATPase activity, coupled |
| GO:0004333 | 0.421 | 0.997 | | | 0.709 | fumarate hydratase activity |
| GO:0030234 | 0.787 | 0.615 | | | 0.701 | enzyme regulator activity |
| GO:0004725 | 0.338 | 0.999 | | | 0.669 | protein tyrosine phosphatase activity |
| GO:0017171 | 0.416 | 0.921 | | | 0.669 | serine hydrolase activity |
| GO:0047429 | 0.389 | 0.904 | | | 0.647 | nucleoside-triphosphate diphosphatase activity |
| GO:0043492 | 0.290 | 0.980 | | | 0.635 | ATPase activity, coupled to movement of substances |
| GO:0015666 | 0.245 | 0.989 | | | 0.617 | restriction endodeoxyribonuclease activity |
| GO:0042625 | 0.200 | 0.996 | | | 0.598 | ATPase activity, coupled to transmembrane movement of ions |
| GO:0005198 | 0.173 | 0.989 | | | 0.581 | structural molecule activity |
| GO:0017111 | 0.220 | 0.925 | | | 0.573 | nucleoside-triphosphatase activity |