| GO:0016829 | 0.955 | 0.953 | | | 0.954 | lyase activity |
| GO:0009036 | 0.081 | 0.975 | | | 0.528 | Type II site-specific deoxyribonuclease activity |
| GO:0015666 | 0.077 | 0.973 | | | 0.525 | restriction endodeoxyribonuclease activity |
| GO:0016836 | 0.006 | 0.980 | | | 0.493 | hydro-lyase activity |
| GO:0016876 | 0.004 | 0.972 | | | 0.488 | ligase activity, forming aminoacyl-tRNA and related compounds |
| GO:0016875 | 0.000 | 0.973 | | | 0.486 | ligase activity, forming carbon-oxygen bonds |
| GO:0004812 | 0.002 | 0.970 | | | 0.486 | aminoacyl-tRNA ligase activity |
| GO:0008289 | 0.155 | 0.796 | | | 0.475 | lipid binding |
| GO:0008270 | 0.000 | 0.949 | | | 0.475 | zinc ion binding |
| GO:0004553 | 0.066 | 0.864 | | | 0.465 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0016491 | 0.000 | 0.923 | | | 0.462 | oxidoreductase activity |
| GO:0016874 | 0.002 | 0.921 | | | 0.462 | ligase activity |
| GO:0016888 | 0.000 | 0.839 | | | 0.420 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0009008 | 0.000 | 0.778 | | | 0.389 | DNA-methyltransferase activity |
| GO:0016453 | 0.000 | 0.769 | | | 0.385 | C-acetyltransferase activity |
| GO:0046961 | 0.003 | 0.728 | | | 0.366 | hydrogen ion transporting ATPase activity, rotational mechanism |
| GO:0016563 | 0.000 | 0.728 | | | 0.364 | transcription activator activity |
| GO:0046873 | 0.000 | 0.686 | | | 0.343 | metal ion transmembrane transporter activity |
| GO:0008080 | 0.614 | 0.025 | | | 0.319 | N-acetyltransferase activity |
| GO:0016835 | 0.254 | 0.384 | | | 0.319 | carbon-oxygen lyase activity |