| GO:0015238 | 1.000 | 0.998 | | | 0.999 | drug transporter activity |
| GO:0031176 | 0.972 | 0.988 | | | 0.980 | endo-1,4-beta-xylanase activity |
| GO:0008171 | 0.950 | 0.999 | | | 0.975 | O-methyltransferase activity |
| GO:0005343 | 0.962 | 0.985 | | | 0.973 | organic acid:sodium symporter activity |
| GO:0015293 | 0.932 | 0.996 | | | 0.964 | symporter activity |
| GO:0015932 | 0.928 | 0.998 | | | 0.963 | nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity |
| GO:0008484 | 0.948 | 0.971 | | | 0.960 | sulfuric ester hydrolase activity |
| GO:0016820 | 0.943 | 0.974 | | | 0.959 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
| GO:0016655 | 0.921 | 0.995 | | | 0.958 | oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
| GO:0015149 | 0.953 | 0.953 | | | 0.953 | hexose transmembrane transporter activity |
| GO:0009036 | 0.886 | 0.999 | | | 0.943 | Type II site-specific deoxyribonuclease activity |
| GO:0046992 | 0.878 | 0.991 | | | 0.935 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0042578 | 0.859 | 0.997 | | | 0.928 | phosphoric ester hydrolase activity |
| GO:0045340 | 0.949 | 0.903 | | | 0.926 | mercury ion binding |
| GO:0015197 | 0.820 | 0.998 | | | 0.909 | peptide transporter activity |
| GO:0015144 | 0.819 | 0.995 | | | 0.907 | carbohydrate transmembrane transporter activity |
| GO:0016893 | 0.812 | 0.996 | | | 0.904 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0004725 | 0.782 | 0.999 | | | 0.890 | protein tyrosine phosphatase activity |
| GO:0004222 | 0.775 | 0.997 | | | 0.886 | metalloendopeptidase activity |
| GO:0015405 | 1.000 | 0.755 | | | 0.877 | P-P-bond-hydrolysis-driven transmembrane transporter activity |