| GO:0016893 | 0.915 | 0.996 | | | 0.956 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0003774 | 0.941 | 0.941 | | | 0.941 | motor activity |
| GO:0016772 | 0.925 | 0.931 | | | 0.928 | transferase activity, transferring phosphorus-containing groups |
| GO:0008233 | 0.964 | 0.855 | | | 0.910 | peptidase activity |
| GO:0004888 | 0.816 | 0.998 | | | 0.907 | transmembrane receptor activity |
| GO:0008237 | 1.000 | 0.774 | | | 0.887 | metallopeptidase activity |
| GO:0003887 | 0.759 | 0.953 | | | 0.856 | DNA-directed DNA polymerase activity |
| GO:0034061 | 0.795 | 0.817 | | | 0.806 | DNA polymerase activity |
| GO:0016788 | 0.641 | 0.967 | | | 0.804 | hydrolase activity, acting on ester bonds |
| GO:0004806 | 0.620 | 0.919 | | | 0.770 | triacylglycerol lipase activity |
| GO:0009008 | 0.499 | 0.897 | | | 0.698 | DNA-methyltransferase activity |
| GO:0009036 | 0.989 | 0.405 | | | 0.697 | Type II site-specific deoxyribonuclease activity |
| GO:0004252 | 0.981 | 0.411 | | | 0.696 | serine-type endopeptidase activity |
| GO:0003700 | 0.410 | 0.975 | | | 0.693 | transcription factor activity |
| GO:0015666 | 0.999 | 0.379 | | | 0.689 | restriction endodeoxyribonuclease activity |
| GO:0004518 | 0.879 | 0.475 | | | 0.677 | nuclease activity |
| GO:0008236 | 0.882 | 0.458 | | | 0.670 | serine-type peptidase activity |
| GO:0022892 | 0.328 | 0.972 | | | 0.650 | substrate-specific transporter activity |
| GO:0017171 | 0.830 | 0.424 | | | 0.627 | serine hydrolase activity |
| GO:0008270 | 0.279 | 0.949 | | | 0.614 | zinc ion binding |