| GO:0008168 | 1.000 | 0.979 | | | 0.990 | methyltransferase activity |
| GO:0016741 | 0.969 | 0.977 | | | 0.973 | transferase activity, transferring one-carbon groups |
| GO:0015666 | 0.916 | 0.939 | | | 0.928 | restriction endodeoxyribonuclease activity |
| GO:0008171 | 0.732 | 0.996 | | | 0.864 | O-methyltransferase activity |
| GO:0008649 | 0.612 | 0.997 | | | 0.804 | rRNA methyltransferase activity |
| GO:0008757 | 0.354 | 0.984 | | | 0.669 | S-adenosylmethionine-dependent methyltransferase activity |
| GO:0008276 | 0.343 | 0.994 | | | 0.668 | protein methyltransferase activity |
| GO:0016722 | 0.913 | 0.360 | | | 0.637 | oxidoreductase activity, oxidizing metal ions |
| GO:0048037 | 0.308 | 0.954 | | | 0.631 | cofactor binding |
| GO:0016433 | 0.234 | 0.998 | | | 0.616 | rRNA (adenine) methyltransferase activity |
| GO:0000179 | 0.228 | 1.000 | | | 0.614 | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
| GO:0046870 | 0.957 | 0.219 | | | 0.588 | cadmium ion binding |
| GO:0008173 | 0.182 | 0.991 | | | 0.586 | RNA methyltransferase activity |
| GO:0009036 | 0.738 | 0.405 | | | 0.571 | Type II site-specific deoxyribonuclease activity |
| GO:0008170 | 0.115 | 0.989 | | | 0.552 | N-methyltransferase activity |
| GO:0005337 | 0.826 | 0.248 | | | 0.537 | nucleoside transmembrane transporter activity |
| GO:0015149 | 0.839 | 0.197 | | | 0.518 | hexose transmembrane transporter activity |
| GO:0008236 | 0.714 | 0.286 | | | 0.500 | serine-type peptidase activity |
| GO:0016436 | 0.000 | 0.997 | | | 0.499 | rRNA (uridine) methyltransferase activity |
| GO:0003998 | 0.950 | 0.047 | | | 0.498 | acylphosphatase activity |