| GO:0004872 | 0.897 | 0.833 | | | 0.865 | receptor activity |
| GO:0004871 | 0.930 | 0.687 | | | 0.809 | signal transducer activity |
| GO:0060089 | 0.733 | 0.725 | | | 0.729 | molecular transducer activity |
| GO:0009036 | 0.994 | 0.405 | | | 0.699 | Type II site-specific deoxyribonuclease activity |
| GO:0015666 | 1.000 | 0.379 | | | 0.689 | restriction endodeoxyribonuclease activity |
| GO:0016722 | 0.958 | 0.360 | | | 0.659 | oxidoreductase activity, oxidizing metal ions |
| GO:0022804 | 0.300 | 0.976 | | | 0.638 | active transmembrane transporter activity |
| GO:0008236 | 0.968 | 0.280 | | | 0.624 | serine-type peptidase activity |
| GO:0015932 | 0.989 | 0.220 | | | 0.604 | nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity |
| GO:0005337 | 0.936 | 0.248 | | | 0.592 | nucleoside transmembrane transporter activity |
| GO:0046870 | 0.940 | 0.219 | | | 0.580 | cadmium ion binding |
| GO:0016888 | 0.997 | 0.152 | | | 0.575 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
| GO:0016820 | 0.136 | 0.974 | | | 0.555 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
| GO:0004536 | 0.578 | 0.518 | | | 0.548 | deoxyribonuclease activity |
| GO:0016876 | 0.118 | 0.972 | | | 0.545 | ligase activity, forming aminoacyl-tRNA and related compounds |
| GO:0004519 | 0.378 | 0.681 | | | 0.530 | endonuclease activity |
| GO:0004252 | 0.432 | 0.604 | | | 0.518 | serine-type endopeptidase activity |
| GO:0015149 | 0.814 | 0.197 | | | 0.505 | hexose transmembrane transporter activity |
| GO:0016887 | 0.036 | 0.968 | | | 0.502 | ATPase activity |
| GO:0015405 | 0.011 | 0.989 | | | 0.500 | P-P-bond-hydrolysis-driven transmembrane transporter activity |