| GO:0034061 | 1.000 | 0.997 | | | 0.999 | DNA polymerase activity |
| GO:0004527 | 1.000 | 0.996 | | | 0.998 | exonuclease activity |
| GO:0003887 | 1.000 | 0.996 | | | 0.998 | DNA-directed DNA polymerase activity |
| GO:0008408 | 1.000 | 0.995 | | | 0.997 | 3'-5' exonuclease activity |
| GO:0004518 | 1.000 | 0.985 | | | 0.993 | nuclease activity |
| GO:0016788 | 1.000 | 0.967 | | | 0.984 | hydrolase activity, acting on ester bonds |
| GO:0003677 | 0.999 | 0.950 | | | 0.975 | DNA binding |
| GO:0016779 | 0.973 | 0.970 | | | 0.972 | nucleotidyltransferase activity |
| GO:0015666 | 0.997 | 0.937 | | | 0.967 | restriction endodeoxyribonuclease activity |
| GO:0016772 | 0.954 | 0.931 | | | 0.942 | transferase activity, transferring phosphorus-containing groups |
| GO:0016855 | 0.849 | 0.998 | | | 0.923 | racemase and epimerase activity, acting on amino acids and derivatives |
| GO:0031419 | 0.952 | 0.851 | | | 0.902 | cobalamin binding |
| GO:0016462 | 0.872 | 0.922 | | | 0.897 | pyrophosphatase activity |
| GO:0016791 | 0.828 | 0.893 | | | 0.861 | phosphatase activity |
| GO:0009008 | 0.870 | 0.721 | | | 0.796 | DNA-methyltransferase activity |
| GO:0016298 | 0.637 | 0.909 | | | 0.773 | lipase activity |
| GO:0004803 | 0.607 | 0.930 | | | 0.768 | transposase activity |
| GO:0046992 | 0.583 | 0.924 | | | 0.754 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0009036 | 0.995 | 0.405 | | | 0.700 | Type II site-specific deoxyribonuclease activity |
| GO:0051002 | 0.447 | 0.901 | | | 0.674 | ligase activity, forming nitrogen-metal bonds |