| GO:0015238 | 1.000 | 0.998 | | | 0.999 | drug transporter activity |
| GO:0016652 | 0.992 | 0.998 | | | 0.995 | oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor |
| GO:0015405 | 1.000 | 0.989 | | | 0.994 | P-P-bond-hydrolysis-driven transmembrane transporter activity |
| GO:0022804 | 0.995 | 0.976 | | | 0.986 | active transmembrane transporter activity |
| GO:0031176 | 0.972 | 0.988 | | | 0.980 | endo-1,4-beta-xylanase activity |
| GO:0008171 | 0.950 | 0.996 | | | 0.973 | O-methyltransferase activity |
| GO:0005343 | 0.962 | 0.985 | | | 0.973 | organic acid:sodium symporter activity |
| GO:0005351 | 0.947 | 0.993 | | | 0.970 | sugar:hydrogen symporter activity |
| GO:0015932 | 0.928 | 0.998 | | | 0.963 | nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity |
| GO:0016820 | 0.943 | 0.974 | | | 0.959 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
| GO:0008484 | 0.948 | 0.967 | | | 0.957 | sulfuric ester hydrolase activity |
| GO:0015149 | 0.953 | 0.953 | | | 0.953 | hexose transmembrane transporter activity |
| GO:0009036 | 0.886 | 0.999 | | | 0.943 | Type II site-specific deoxyribonuclease activity |
| GO:0046992 | 0.878 | 0.991 | | | 0.935 | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |
| GO:0031419 | 0.869 | 0.996 | | | 0.933 | cobalamin binding |
| GO:0042578 | 0.859 | 0.997 | | | 0.928 | phosphoric ester hydrolase activity |
| GO:0016722 | 0.872 | 0.982 | | | 0.927 | oxidoreductase activity, oxidizing metal ions |
| GO:0045340 | 0.949 | 0.903 | | | 0.926 | mercury ion binding |
| GO:0070001 | 0.834 | 1.000 | | | 0.917 | aspartic-type peptidase activity |
| GO:0016791 | 0.837 | 0.996 | | | 0.916 | phosphatase activity |